Conformational and functional properties of peptides covering the intersubunit region of influenza virus hemagglutinin

Download
  1. Get@NRC: Conformational and functional properties of peptides covering the intersubunit region of influenza virus hemagglutinin (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1111/j.1432-1033.1992.tb16942.x
AuthorSearch for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titleEuropean Journal of Biochemistry
ISSN1742-4658
Volume206
Issue2
Pages421425; # of pages: 5
AbstractThe functionally active part of influenza virus hemagglutinin was investigated through the synthesis of a series of peptides representing different parts of the intersubunit region. Secondary structure prediction, circular dichroism and Fourier transform infrared spectroscopic studies were undertaken to investigate the secondary structure of these peptides. The peptide fragments were found to adopt multiple conformations, depending on their concentration in solution, the presence of the non-ionic detergent octyl-β-d-glucoside and the polarity of the solvent. The results of biological studies with these peptide fragments are discussed in relation to their conformation, as inferred from the spectroscopic analysis.
Publication date
PublisherJohn Wiley & Sons, Inc.
LanguageEnglish
AffiliationNRC Steacie Institute for Molecular Sciences; National Research Council Canada
Peer reviewedYes
NRC number36
NPARC number9147803
Export citationExport as RIS
Report a correctionReport a correction
Record identifier03e06b69-e29f-49e5-a736-4da2463b4df1
Record created2009-06-25
Record modified2016-12-13
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)