Vitamin E remains the major lipid-soluble, chain-breaking antioxidant in human plasma even in individuals suffering severe vitamin E deficiency

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DOIResolve DOI: http://doi.org/10.1016/0003-9861(87)90489-9
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TypeArticle
Journal titleArchives of Biochemistry and Biophysics
ISSN0003-9861
Volume259
Issue1
Pages224225; # of pages: 2
Subjectalpha tocopherol; antioxidant; alpha tocopherol deficiency; blood and hemopoietic system; etiology; human; human cell; plasma; Antioxidants; Human; Lipids; Solubility; Support, Non-U.S. Gov't; Vitamin E; Vitamin E Deficiency
AbstractThe chain-breaking (peroxyl radical-trapping) antioxidant activity of plasma obtained from several patients with a very severe vitamin E deficiency has been measured. The total chain-breaking antioxidant activity in lipid extracts has been shown to be approximately equal to the concentration of vitamin E. For whole plasma there is no significant difference in the concentrations of water-soluble, chain-breaking antioxidants between the E-deficient patients and healthy adults. It is concluded that even in cases of very severe vitamin E deficiency the requirement for this vitamin is not met by some other exogenous or endogenous antioxidant. © 1987.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC)
Peer reviewedYes
NPARC number21276644
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Record identifier0433835e-ff01-4e63-a8d7-40d46d8563d0
Record created2015-10-13
Record modified2016-05-09
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