The crystal and molecular structure of DL-alphaprodine hydrochloride

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DOIResolve DOI: http://doi.org/10.1107/S0365110X60001308
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TypeArticle
Journal titleActa Crystallographica
ISSN0365-110X
Volume13
Issue7
Pages525531; # of pages: 7
AbstractThe structure of the hydrochloride DL-alphaprodine has been determined by the isomorphous replacement method with the aid of data for the hydrobromide. Zero-level normal, and first-level generalized, projections along the three axes have been employed. The structure has been refined by three-dimensional Fourier and differential syntheses. The stereochemical configuration found for the alphaprodine molecule agrees with that of one of four possible isomers and confirms that proposed by Beckett and co-workers on conformational and other grounds. The piperidine ring has the chair form with the phenyl ring equatorial and the propionoxy chain axial; the methyl group on C(3) is trans to the phenyl ring on C(4).
Publication date
LanguageEnglish
AffiliationNational Research Council Canada
NoteAddendum to this paper available in Acta Crystallographica, Volume 14 (1), January 1961. (NRCC 6054).
Peer reviewedYes
NRC number5621
NPARC number21274957
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Record identifier06d0e467-7a5a-43c2-8b73-9adc5c347317
Record created2015-05-04
Record modified2016-05-09
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