Novel ethyl-derivatization approach for the determination of fluoride by headspace gas chromatography/mass spectrometry

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DOIResolve DOI: http://doi.org/10.1021/ac302303r
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TypeArticle
Journal titleAnalytical Chemistry
ISSN0003-2700
Volume85
Issue2
Pages877881; # of pages: 5
SubjectAdverse effect; Batch reactions; Certified reference materials; Closed vessels; Derivatizations; Fluoride ion; Gas chromatography/Mass spectrometry; Headspace gas chromatography; Headspaces; Limit of detection; Linear range; Non-volatile; One-step reactions; Standard addition; Tap water; Tetrachloroferrate; Chromatography; Iron compounds; Organic solvents; Seawater; Spectrometry
AbstractWe report a novel derivatization chemistry for determination of fluoride based on the batch reaction of fluoride ions with triethyloxonium tetrachloroferrate(III) in a closed vessel to yield fluoroethane. Gaseous fluoroethane was readily separated from the matrix, sampled from the headspace, and determined by gas chromatography/mass spectrometry. The method was validated using rainwater certified reference material (IRMM CA408) and subsequently applied to the determination of fluoride in various matrixes, including tap water, seawater, and urine. An instrumental limit of detection of 3.2 μg/L with a linear range up to 50 mg/L was achieved. The proposed derivatization is a one-step reaction, requires no organic solvents, and is safe, as the derivatizing agent is nonvolatile. Determination of fluoride is affected by common fluoride-complexing agents, such as Al(III) and Fe(III). The effect of large amounts of these interferences was studied, and the adverse effect of these ions was eliminated by use of the method of standard additions.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; Measurement Science and Standards; Security and Disruptive Technologies
Peer reviewedYes
NPARC number21270353
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Record identifier09525e2a-5f5b-486b-8ef4-838601e78703
Record created2014-02-04
Record modified2016-05-09
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