Chemical structures and bioactivities of sulfated polysaccharides from marine algae

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DOIResolve DOI: http://doi.org/10.3390/md9020196
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TypeArticle
Journal titleMarine Drugs
Volume9
Issue2
Pages196223; # of pages: 28
Subjectsulfated polysaccharide; marine macroalgae; carbohydrate structure; bioactivity; oligosaccarides
AbstractSulfated polysaccharides and their lower molecular weight oligosaccharide derivatives from marine macroalgae have been shown to possess a variety of biological activities. The present paper will review the recent progress in research on the structural chemistry and the bioactivities of these marine algal biomaterials. In particular, it will provide an update on the structural chemistry of the major sulfated polysaccharides synthesized by seaweeds including the galactans (e.g., agarans and carrageenans), ulvans and fucans. It will then review the recent findings on the anticoagulant/antithrombotic, antiviral, immuno-inflammatory, antilipidemic and antioxidant activities of sulfated polysaccharides and their potential for therapeutic application.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Marine Biosciences; NRC Institute for Nutrisciences and Health
Peer reviewedYes
NRC number51801
NPARC number19613697
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Record identifier09b55d41-b225-4af3-b7da-bcd2cf892777
Record created2012-03-06
Record modified2016-05-09
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