Comparison of different infrared measurement techniques in the clinical analysis of biofluids

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DOIResolve DOI: http://doi.org/10.1016/0165-9936(96)00037-4
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TypeArticle
Journal titleTrAC Trends in Analytical Chemistry
ISSN0165-9936
Volume15
Issue7
Pages286296; # of pages: 11
AbstractAn infrared spectroscopy-based multicomponent assay of biofluids such as whole blood, urine, and synovial fluid holds considerable promise for the clinical laboratory. The methodology is reagentless, fast and readily automated. Infrared spectroscopic analysis is not hindered by the physical state of the sample and measurements can be made in a variety of instrument configurations. In this review we present the spectra of physiological samples measured as liquids and dried films using transmission-, attenuated total reflection-, photoacoustic-and diffuse reflectance infrared spectroscopy. The advantages and limitations of each of these techniques are discussed in the context of developing a routine clinical analysis method for biofluid samples.
Publication date
PublisherElsevier Science B.V.
LanguageEnglish
AffiliationNRC Institute for Biodiagnostics; National Research Council Canada
Peer reviewedYes
NRC number412
NPARC number9148195
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Record identifier13d77254-94d5-4db8-aa46-870b28e49c71
Record created2009-06-25
Record modified2016-11-07
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