Synthesis and biological evaluation of ether bridged bicyclic iminosugar derivatives

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DOIResolve DOI: http://doi.org/10.1016/j.carres.2009.05.029
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TypeArticle
Journal titleCarbohydrate Research
Volume344
Issue13
Pages16391645; # of pages: 7
SubjectBicyclic; Iminosugar; Ether bridge; C-Glycoside; Glycosidase
AbstractBicyclic iminosugar derivatives with an ether bridge bearing different substituents on C-2 and the nitrogen atom have been synthesized from a C-glycoside bearing an isopropylidene acetal. The activities of these compounds were investigated against several glycosidase enzymes and showed moderate inhibition and activation.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Institute for Biological Sciences
Peer reviewedYes
NPARC number15329249
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Record identifier1ce4f5be-d26f-4ca1-92a2-320d0ef45c92
Record created2010-05-21
Record modified2016-05-09
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