Silicon-on-insulator guided mode resonance grating for evanescent field molecular sensing

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DOIResolve DOI: http://doi.org/10.1364/OE.17.018371
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TypeArticle
Journal titleOptic Express
Volume17
Issue20
Pages1837118380; # of pages: 9
Subjectsilicon; molecular; monolayer; protein
AbstractWe present experimental and theoretical results of label-free molecular sensing using the transverse magnetic mode of a 0.22 μm thick silicon slab waveguide with a surface grating implemented in a guided mode resonance configuration. Due to the strong overlap of the evanescent field of the waveguide mode with a molecular layer attached to the surface, these sensors exhibit high sensitivity, while their fabrication and packaging requirements are modest. Experimentally, we demonstrate a resonance wavelength shift of ~1 nm when a monolayer of the protein streptavidin is attached to the surface, in good agreement with calculations based on rigorous coupled wave analysis. In our current optical setup this shift corresponds to an estimated limit of detection of 0.2% of a monolayer of streptavidin.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Institute for Microstructural Sciences; NRC Steacie Institute for Molecular Sciences
Peer reviewedYes
NPARC number16096610
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Record identifier1f071ff5-039e-4cac-9a60-afb32e1d9ecf
Record created2010-09-27
Record modified2016-05-09
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