Delivery of drugs and biomolecules using carbon nanotubes

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DOIResolve DOI: http://doi.org/10.1016/j.carbon.2011.05.049
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TypeArticle
Journal titleCarbon
Volume49
Issue13
Pages40774097; # of pages: 21
AbstractCarbon nanotubes (CNTs) have emerged as one of the most advanced nanovectors for the highly efficient delivery of drugs and biomolecules. They offer several appealing features such as large surface areas with well defined physico-chemical properties as well as unique optical and electrical properties. They can be conjugated non-covalently or covalently with drugs, biomolecules and nanoparticles. Albeit some pending concerns about their toxicity in vitro and in vivo, functionalized CNTs appear to exhibit very low toxicity and are not immunogenic. Thus, they could be promising carriers with a great potential for the development of a new-generation delivery system for drugs and biomolecules. There have been significant advances in the field of CNT-based drug delivery, especially in the specific targeting of anticancer and anti-inflammatory drugs for tissues and organs in the body, where their therapeutic effect is highly required. Other promising applications are the delivery of DNA, RNA and proteins.
Publication date
PublisherElsevier
LanguageEnglish
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedYes
NRC number53370
NPARC number18518905
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Record identifier1f94e4c3-a307-4449-8257-ce3180225100
Record created2012-03-06
Record modified2016-05-09
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