Co-localization and interaction of DPYSL3 and GAP43 in primary cortical neurons: Biochem.Biophys.Res.Commun.

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TypeArticle
Journal titleBiochem.Biophys.Res.Commun.
Volume363
Issue1
Pages190193; # of pages: 4
SubjectAnimals; assay; Canada; Cells,Cultured; GAP-43 Protein; interaction; metabolism; Nerve Tissue Proteins; Neurons; protein; Protein Interaction Mapping; Rats; Rats,Sprague-Dawley; Subcellular Fractions
AbstractDihydropyrimidinase-like 3 (DPYSL3) and GAP43 are both involved in neurite outgrowth, a crucial process for the differentiation of neurons. The present study shows for the first time that DPYSL3 co-localizes with GAP43 in primary cortical neurons. Further co-immunoprecipitation and overlay assay showed the ability of both recombinant and endogenous DPYSL3 to bind GAP43, indicating a specific interaction between DPYSL3 and GAP43 in primary cortical neurons
Publication date
LanguageEnglish
AffiliationNRC Institute for Biological Sciences; National Research Council Canada
Peer reviewedNo
NRC numberKOWARA2007
NPARC number9365080
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Record identifier25713f6f-8d86-4658-8a76-8e3920f071e4
Record created2009-07-10
Record modified2016-05-09
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