Diversity-based organic synthesis in the era of genomics and proteomics

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DOIResolve DOI: http://doi.org/10.1002/1521-3773(20010119)40:2<339::AID-ANIE339>3.0.CO;2-J
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TypeArticle
Journal titleAngewandte Chemie - International Edition
Volume40
Issue2
Pages339346; # of pages: 8
Subjectcombinatorial chemistry; heterocycles; molecular diversity; natural products; solid-phase synthesis
AbstractIs the game over or has it just begun? The technical advances related to genomics and proteomics research have provided the scientific community with large sets of sequence-level genetic information with enormous potential for identification of new drug targets. Gene expression and genome-wide gene sequencing have been successfully accomplished. What is the next step? What will be done with this information? Challenges faced are to identify genes or proteins of interest and to determine the functions of a given gene or protein that we only know at the sequence level at the moment.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Steacie Institute for Molecular Sciences
Peer reviewedNo
NPARC number12339052
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Record identifier275ff0d3-4b9f-4897-bcca-862f555ec7a4
Record created2009-09-11
Record modified2016-05-09
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