117 POSTER ANG1005, Paclitaxel conjugated to the angiopep brain transport vector for the treatment of brain cancer: preclinical studies

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DOIResolve DOI: http://doi.org/10.1016/S1359-6349(08)72049-4
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TypeArticle
Proceedings titleEuropean Journal of Cancer Supplements
Conference20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Oct. 22, 2008
ISSN1359-6349
Pages3839; # of pages: 2
Subjectblood-brain barrier; Paclitaxel; ANG1005; glioblastoma; drug delivery technology
AbstractIn situ brain perfusion were used to assess the brain uptake of our conjugates. Analysis of tissues was done after extraction by LC-MS-MS or HPLC. Xenograft models of glioblastoma (U87) were established by intercranial stereotaxic injections of U87 cells in mice and rats.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada
Peer reviewedYes
NPARC number21275174
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Record identifier2d20c5a7-cacb-4b13-87da-c16773a45e99
Record created2015-05-22
Record modified2016-05-09
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