Intravascular optical coherence tomography to characterize tissue deformation during angioplasty : preliminary experiments with artery phantoms

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DOIResolve DOI: http://doi.org/10.1117/1.JBO.17.9.096015
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TypeArticle
Journal titleJournal of Biomedical Optics
ISSN1083-3668
Volume17
Issue9
Pages096015-1096015-7
SubjectAngioplasty; Optical coherence tomography; Tissue characterization
AbstractWe explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was performed to extract the inner and outer diameters of the phantoms at various pressures. The goal for the second scenario was twofold. First, we investigated the IVOCT capability to monitor a more complex balloon inflation process. The balloon was in a folded state prior to inflation. This allowed studying two stages of deformation: during balloon unfolding and during balloon expansion. Second, we investigated IVOCT capability to monitor the deformation in a three-layer phantom used to better mimic a true artery. So, not only were the IVOCT images processed to provide the inner and outer diameters of the phantom, but the layer thicknesses were also determined. In both scenarios, IVOCT monitoring revealed to be very efficient in providing relevant information about the phantom deformation during balloon inflation.
Publication date
LanguageEnglish
AffiliationEnergy, Mining and Environment; National Research Council Canada
Peer reviewedYes
NRC numberNRC-EME-53136
NPARC number21268529
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Record identifier2db7f483-5d2f-4494-8633-a1908cdbb24d
Record created2013-09-12
Record modified2016-05-09
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