Mechanical and microstructural characterization of 45S5 Bioglass® scaffolds for tissue engineering

Download
  1. Get@NRC: Mechanical and microstructural characterization of 45S5 Bioglass® scaffolds for tissue engineering (Opens in a new window)
AuthorSearch for: ; Search for: ; Search for: ; Search for:
TypeArticle
Proceedings titleCeramic Transactions
ConferenceNext Generation Biomaterials and Surface Properties of Biomaterials Symposia - Materials Science and Technology 2011 Conference and Exhibition, MS and T 2011, 16 October 2011 through 20 October 2011, Columbus, OH
ISSN1042-1122
ISBN9781118273326
Volume237
Pages19; # of pages: 9
Subject45S5 bioglass; Bone ingrowth; Dry powders; Micro-structural characterization; National Research Council; Powder mixtures; Primary phase; Scaffolds for tissue engineering; Secondary phase; Biological materials; Bone; Ceramic foams; Characterization; Powder metallurgy; Sintering; Sodium; Surface properties; Bioactive glass
AbstractBioglass® 45S5 is the most widely investigated bioactive glass. It was recently demonstrated that this glass is better integrated into bone when the structure is porous. The National Research Council Canada has recently developed a process to produce metallic and ceramic foams using a powder metallurgy approach. Preliminary tests showed that Bioglass® foams can be produced with this process. These foams are produced by foaming a powder mixture composed of Bioglass® particles, a binder and a foaming agent. Highly porous Bioglass® foams (64-79% porosity) were successfully synthesized from dry powder blends. The porosity of the resulting foams was open and the pore size was essentially between 175 and 880 μm in diameter, as required for bone ingrowth. During sintering, crystallization took place and Na6Ca 3Si6O18 (primary phase) and Na 2Ca4(PO4)2SiO4 (secondary phase) were observed. The mechanical compressive strength ranged from 1.7 to 5.5 MPa.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Industrial Materials Institute (IMI-IMI)
Peer reviewedYes
NPARC number21269353
Export citationExport as RIS
Report a correctionReport a correction
Record identifier2e2db8db-332a-44d1-a5b1-f7e3d6b1a98d
Record created2013-12-12
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)