At the frontiers of surgery: Review

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DOIResolve DOI: http://doi.org/10.1186/1758-3284-3-7
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TypeArticle
Journal titleHead and Neck Oncology
ISSN1758-3284
Volume3
Issue1
Article number7
Subjectclinical examination; conference paper; diagnostic accuracy; head and neck disease; high risk patient; histopathology; human; lung disease; mouth disease; optical coherence tomography; optical diagnostic technology; optics; photodynamic therapy; plastic surgery; priority journal; prognosis; Raman spectrometry; surgical technology; therapy effect; biopsy; diagnostic procedure; general surgery; head; instrumentation; methodology; neck; pathology; photochemotherapy; utilization review; Biopsy; Diagnostic Techniques and Procedures; General Surgery; Head; Humans; Neck; Photochemotherapy; Tomography, Optical Coherence
AbstractThe complete surgical removal of disease is a desirable outcome particularly in oncology. Unfortunately much disease is microscopic and difficult to detect causing a liability to recurrence and worsened overall prognosis with attendant costs in terms of morbidity and mortality. It is hoped that by advances in optical diagnostic technology we could better define our surgical margin and so increase the rate of truly negative margins on the one hand and on the other hand to take out only the necessary amount of tissue and leave more unaffected non-diseased areas so preserving function of vital structures. The task has not been easy but progress is being made as exemplified by the presentations at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS) in San Francisco in January 2010. We review the salient advances in the field and propose further directions of investigation. © 2011 Upile et al; licensee BioMed Central Ltd.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Institute for Biodiagnostics (IBD-IBD)
Peer reviewedYes
NPARC number21271581
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Record identifier2f2116f3-bef2-443e-b806-e133fd83ba60
Record created2014-03-24
Record modified2016-05-09
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