Learning related activation of somatosensory cortex by an auditory stimulus recorded with magnetoencephalography

Download
  1. (PDF, 433 KB)
  2. Get@NRC: Learning related activation of somatosensory cortex by an auditory stimulus recorded with magnetoencephalography (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1016/j.neuroimage.2010.06.005
AuthorSearch for: ; Search for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titleNeuroImage
Volume53
Issue1
Pages275282; # of pages: 8
SubjectClassical conditioning; Learning; Cross-modal; Somatosensory; Induced responses
AbstractAdvances in non-invasive neuroimaging technology now provide a means of directly observing learning within the brain. Classical conditioning serves as an ideal starting point for examining the dynamic expression of learning within the human brain, since this paradigm is well characterized using multiple levels of analysis in a broad range of species. We used MEG to expand the characterization of conditioned responses (CR) recorded from the human brain with a simultaneous examination of their spatial, temporal and spectral properties. We paired an auditory conditioned stimulus (CS+) with a somatosensory unconditioned stimulus (US). We found that when the US was randomly omitted, presentations of CS+ alone, elicited greater desynchronization of beta-band activity in contralateral somatosensory cortex compared to presentations of an auditory stimulus that was never paired with the US (CS−), and compared the CS+ following a non-reinforced extinction session. This differentiation was largest between 150 and 350 ms following US omission. We show that cross-modal CRs in the primary sensorimotor system are predominantly characterized by modulation of ongoing cortical oscillations.
Publication date
LanguageEnglish
AffiliationNRC Institute for Biodiagnostics; National Research Council Canada
Peer reviewedYes
NPARC number17712970
Export citationExport as RIS
Report a correctionReport a correction
Record identifier34bda5f0-2a57-479d-8e44-257c47ce1d1e
Record created2011-04-09
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)