Applications of visible-near infrared spectroscopy in burn injury assessment

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DOIResolve DOI: http://doi.org/10.1117/12.384955
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TypeArticle
Proceedings titleBiomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques
Series titleProceedings of SPIE; Volume 3918
ConferenceBiomedical Spectroscopy : Vibrational Spectroscopy and Other Novel Techniques, January 22, 2000; San Jose, California, USA
ISSN0277-786X
Pages8390; # of pages: 8
Subjectnear infrared; spectroscopy; cutaneous burns; multivariate analysis
AbstractThe major objective of the project is to develop a noninvasive method to assess thermal burns. Currently, the diagnosis relies primarily upon visual assessment of the injury by a burn specialist and/or plastic surgeon. The diagnosis is based on the surface appearance of the wound to determine the type or depth of the burn. Near IR spectroscopic measurements of injured tissue provide an objective means of distinguishing between surface and subsurface changes related to the tissue injury. An acute porcine model is employed to investigate the potential of near IR spectroscopy to accurately distinguish between burns of varying severity in the early postburn period. Parallel factor analysis is used to investigate the spectral changes related to burns of varying severity. Burn injuries drastically alter the physical and optical properties of the tissue. Thermal destruction of cutaneous vasculature disrupts perfusion and oxygen delivery to the affected tissue. Tissue blood oxygenation decreases with increased severity of the burn. The result demonstrate that near IR spectroscopy may provide a new tool for objective clinical assessment of burn injuries.
Publication date
PublisherSPIE
AffiliationNational Research Council Canada; NRC Institute for Biodiagnostics
Peer reviewedYes
NRC number1819
NPARC number9742094
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Record identifier37f913ac-a9c0-43e3-80f2-773f0791f2c0
Record created2009-07-17
Record modified2017-09-13
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