Three new triterpenes from the seeds of Combretum quadrangulare and their hepatoprotective activity

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DOIResolve DOI: http://doi.org/10.1021/np000486x
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TypeArticle
Journal titleJournal of Natural Products
ISSN0163-3864
1520-6025
Volume64
Issue3
Pages360363; # of pages: 4
AbstractThree new triterpenes of the lupane type, 2α,6β-dihydroxybetulinic acid (1) and 6β-hydroxyhovenic acid (2), and an oleanane type, 6β-hydroxyarjunic acid (3), together with several known compounds, have been isolated from the MeOH extract of the seeds of Combretum quadrangulare. The structures of these compounds were elucidated on the basis of spectroscopic analysis, and their hepatoprotective activities were tested for d-GalN/TNF-α-induced cell death in primary cultured mouse hepatocytes.
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LanguageEnglish
Peer reviewedYes
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NPARC number21274810
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Record identifier437d4914-fb8f-4b13-b846-4cabf2d363fe
Record created2015-04-13
Record modified2016-05-09
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