Antimicrobial peptides and their potential as therapeutants in aquaculture

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EditorSearch for: Fletcher, Garth L.; Search for: Rise, Matthew L.
TypeBook Chapter
Book titleAquaculture Biotechnology
Pages105120; # of pages: 16
Subjectantimicrobial peptides; aquaculture therapeutants; teleost fish; innate immune system; AMPs; host defense peptides; AMPs in invertebrates; antiparasitic activity; AMP disease control; trucated mussel defensins
AbstractTeleost fish rely heavily on protective molecules of the innate immune system, of which antimicrobial peptides (AMPs) comprise one component. These small, usually cationic, amphipathic peptides are able to kill microbes very specifically. They are produced mainly by circulating immune cells and epithelial cells of the gut and skin and are often induced in response to infection. These peptides present a new avenue of disease prevention and/or treatment through their administration as therapeutants or via transgenic technology. Current treatments for combating disease in aquacultured organisms, recent advances in applications of AMPs, and future prospects in this field are described.
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AffiliationNational Research Council Canada; NRC Institute for Marine Biosciences
Peer reviewedNo
NRC number42819
NPARC number21268319
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Record identifier45f67e36-aef0-4617-8841-702bcbc177e6
Record created2013-06-19
Record modified2016-06-01
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