Time resolved chromatograms in ultra-thin layer chromatography

  1. Get@NRC: Time resolved chromatograms in ultra-thin layer chromatography (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1016/j.chroma.2012.05.090
AuthorSearch for: ; Search for: ; Search for: ; Search for:
Journal titleJournal of Chromatography A
SubjectPlanar chromatography; Ultrathin-layer chromatography; Time resolved thin layer chromatography; Real-time analysis; Automated color-filtered chromatograms
AbstractUltrathin-layer chromatography (UTLC) is a recently developed analytical method intended for compact, rapid separations of nanolitre analyte volumes. Optimizing this method's performance requires new measurement techniques compatible with the millimetre length scales and rapid separation dynamics observed in UTLC. We have designed, implemented and characterized a measurement system which records UTLC separations in full color with 32 μm spatial resolution and 33 ms temporal resolution. Our code analyzes multiple tracks per plate, filters analyte spots by color, and automatically generates time-resolved figures of merit. The instrument presented here captures a wealth of information from a UTLC separation, and should provide insight into UTLC physics and improved analytical performance.
Publication date
AffiliationSecurity and Disruptive Technologies; National Research Council Canada
Peer reviewedYes
NPARC number21268697
Export citationExport as RIS
Report a correctionReport a correction
Record identifier51fcdd96-02af-40b7-8e69-b838346a6afe
Record created2013-11-07
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)
Date modified: