The glycogen content and its topography and UDP glucose: glycogen α-4 glucosyltransferase (EC 2.4.1.11) activity in rat brain after experimental carbon monoxide intoxication

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DOIResolve DOI: http://doi.org/10.1007/BF00687592
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TypeArticle
Journal titleActa Neuropathologica
ISSN0001-6322
1432-0533
Volume24
Pages222231; # of pages: 10
Subjectcarbon monoxide intoxication; brain; glycogen; UDPG-G glucosyltransferase
AbstractThe glycogen content and its topography and the activity of UDPglucose-glycogen glucosyltransferase in the brain of rats after CO intoxication were investigated. A transient increase in glycogen content and in the enzyme activity was noticed. The highest level of glycogen was observed after 4h and the most significant increase of the enzyme activity after 2h, returning to normal values after 120 h. In the histochemical studies glycogen was deposited in the perivascular astrocytes, in their cytoplasm and astrocytic processes. These changes were localized in the cerebral and cerebellar cortex and in the grey formations of brain stem and were expressed mostly after 4, 6 and 12 h following CO intoxication.
Publication date
PublisherSpringer
LanguageEnglish
AffiliationNRC Institute for Biological Sciences; National Research Council Canada
Peer reviewedYes
NRC numberSMIALEK1973
NPARC number9371802
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Record identifier5942e032-4486-470c-8f45-6c25ae80da41
Record created2009-07-10
Record modified2017-04-11
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