Integration of optical components on-chip for scattering and fluorescence detection in an optofluidic device

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DOIResolve DOI: http://doi.org/10.1364/BOE.3.002784
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TypeArticle
Journal titleBiomedical Optics Express
ISSN2156-7085
Volume3
Issue11
Pages27842793; # of pages: 10
SubjectFluidic components; Fluorescence detection; Functional layer; Microfluidic channel; On chips; Optical components; Optofluidic devices; Photonic components; Reliable detection; Photoexcitation; Fluorescence
AbstractAn optofluidic device is demonstrated with photonic components integrated onto the chip for use in fluorescence and scatter detection and counting applications. The device is fabricated by integrating the optical and fluidic components in a single functional layer. Optical excitation on-chip is accomplished via a waveguide integrated with a system of lenses that reforms the geometry of the beam in the microfluidic channel into a specific shape that is more suitable for reliable detection. Separate counting tests by detecting fluorescence and scattered signals from 2.5 and 6.0 μm beads were performed and found to show detection reliability comparable to that of conventional means of excitation and an improvement over other microchip-based designs. © 2012 Optical Society of America.
Publication date
LanguageEnglish
AffiliationInformation and Communication Technologies; National Research Council Canada
Peer reviewedYes
NPARC number21270060
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Record identifier5c55188c-bf1e-44c7-b956-b2813c52baef
Record created2013-12-18
Record modified2016-05-09
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