Radical-trapping antioxidants in vitro and in vivo

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DOIResolve DOI: http://doi.org/10.1016/0302-4598(87)85024-9
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TypeArticle
Journal titleBioelectrochemistry and Bioenergetics
Volume18
Issue1-3
Pages219229; # of pages: 11
AbstractThe contributions from urate (58% ? 18%), plasma proteins (21% ? 10%), ascorbate (14% ? 8%) and vitamin E (7% ? 2%) to the Total Radical-trapping Antioxidant Parameter (TRAP) of plasma account for all of the peroxyl radical-trapping antioxidant activity in the majority of samples. Time dependent studies show that vitamin E is regenerated or spared during peroxyl radical attack by the water soluble antioxidants. The rates of uptake of dietary RRR- and SRR-[alpha]-tocopherols have been determined using deuterium labelled [alpha]-tocopherol acetates. There is a preferential uptake of the natural, RRR-[alpha]-tocopherol by all tissues (except the liver in the first month). These studies have potential implications for human nutrition.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Chemical Process and Environmental Technology
Peer reviewedNo
NPARC number12328482
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Record identifier619ba49e-3595-414a-92be-79535ea477aa
Record created2009-09-10
Record modified2016-05-09
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