Post-ischemic hypothermia therapy inhibits inflammatory gene transcription and leukocyte recruitment in cerebral microvessels

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TypeArticle
Journal titleCanadian Journal of Anesthesia
Volume52
Issue4
PagesA1A8
AbstractHypothermia therapy improves histological and behavioral outcomes and mortality following global cerebral ischemia in animals and humans. This therapy has potent anti-inflammatory effects but the anti-inflammatory mechanisms are not completely understood. We explored the effect of hypothermia therapy on inflammatory gene transcription and leukocyte recruitment and adhesion in cerebral microvessels following global cerebral ischemia in the mouse.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada
Peer reviewedYes
NPARC number21275317
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Record identifier62d956af-eafc-4f09-9089-bedd80ebeb72
Record created2015-06-09
Record modified2016-05-09
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