The application of 19F magnetic resonance ex vivo imaging of three-dimensional cultured breast cancer cells to study the effect of δ-tocopherol.

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DOIResolve DOI: http://doi.org/10.1016/j.ab.2009.01.010
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TypeArticle
Journal titleAnalytical Biochemistry
Volume387
Issue2
Pages315317; # of pages: 3
AbstractThe aim of this study was to determine the role of delta-tocopherol in breast cancer cell growth ex vivo. Human gland mammary adenocarcinoma (MCF-7) and human T-lymphoblastoid (CEM) cells were cultured in the presence of delta-tocopherol at various concentrations (0-750 microM) for 5 days. We have grown 3D ex vivo breast cancer cell cultures in the hollow fiber bioreactor (HFBR). (19)F magnetic resonance imaging (MRI) was used to evaluate oxygen concentration in the cell suspension and thus its viability.
Publication date
LanguageEnglish
AffiliationNRC Institute for Biodiagnostics; National Research Council Canada
Peer reviewedYes
NPARC number20109991
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Record identifier63166b71-90ba-492d-890c-bc70fb1f8c72
Record created2012-06-09
Record modified2016-05-09
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