Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications

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DOIResolve DOI: http://doi.org/10.1007/s12551-011-0054-7
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TypeArticle
Journal titleBiophysical Reviews
Volume3
Issue3
Pages155169; # of pages: 15
SubjectOptical coherence tomography; Biomedical applications; Signal noise; Time-domain; Fourier-domain; Full-field system; Catheter technology
AbstractThe advances made in the last two decades in interference technologies, optical instrumentation, catheter technology, optical detectors, speed of data acquisition and processing as well as light sources have facilitated the transformation of optical coherence tomography from an optical method used mainly in research laboratories into a valuable tool applied in various areas of medicine and health sciences. This review paper highlights the place occupied by optical coherence tomography in relation to other imaging methods that are used in medical and life science areas such as ophthalmology, cardiology, dentistry and gastrointestinal endoscopy. Together with the basic principles that lay behind the imaging method itself, this review provides a summary of the functional differences between time-domain, spectral-domain and full-field optical coherence tomography, a presentation of specific methods for processing the data acquired by these systems, an introduction to the noise sources that plague the detected signal and the progress made in optical coherence tomography catheter technology over the last decade.
Publication date
LanguageEnglish
AffiliationNRC Institute for Biodiagnostics; NRC Institute for Microstructural Sciences; National Research Council Canada
Peer reviewedYes
NPARC number19726598
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Record identifier70f8baef-21c8-459f-b465-d0e07e28e713
Record created2012-03-28
Record modified2016-05-09
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