Antihistaminic effects of stevia fermenting extracts on isolated ileum from guinea pig

Download
  1. Get@NRC: Antihistaminic effects of stevia fermenting extracts on isolated ileum from guinea pig (Opens in a new window)
AuthorSearch for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titlePharmacometrics
Volume65
Issue5-6
Pages105109; # of pages: 5
SubjectAntihistaminic effects; Histamine-induced contraction; Isolated guinea pig ileum; Stevia fermenting extracts
AbstractStevia rebaudiana Bertoni is a shrub growing originally in Paraguay. The leaves of this plant contain stevinoside, a sweet constituent which is 300 times as sweet as sucrose. Recently, this extracts is clinically useful for IgE related disease, atopic dermatitis or allergic dermatitis. Therefore, we studied the effects of stevia fermenting extracts (Stevia rebaudiana Bertoni) on histamine-induced contractions in isolated ileum from guinea pig. Two stevia extracts (A and C) inhibited the histamine-induced contractions. However, stevia extracts B, D and E did not affect on the histamine-induced contraction. Our results show stevia fermenting extracts having antihistaminic effects (H 1 receptor).
Publication date
LanguageJapanese
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NPARC number21274775
Export citationExport as RIS
Report a correctionReport a correction
Record identifier73097449-ce61-4cff-a26d-ed59b55eed9d
Record created2015-04-08
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)