Purification, functionalization, and bioconjugation of carbon nanotubes

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DOIResolve DOI: http://doi.org/10.1007/978-1-61779-151-2_32
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EditorSearch for: Mark, Sonny S.
TypeBook Chapter
Book titleBioconjugation Protocols
Series titleMethods in Molecular Biology; Volume 751
Pages505532; # of pages: 28
SubjectCarbon nanotunes (CNTs); Gold nanoparticles; Purification; Noncovalent/covalent biofunctionalization
AbstractBioconjugation of carbon nanotubes (CNTs) with biomolecules promises exciting applications such as biosensing, nanobiocomposite formulation, design of drug vector systems, and probing protein interactions. Pristine CNTs, however, are virtually water-insoluble and difficult to evenly disperse in a liquid matrix. Therefore, it is necessary to attach molecules or functional groups to their sidewalls to enable bioconjugation. Both noncovalent and covalent procedures can be used to conjugate CNTs with a target biomolecule for a specific bioapplication. This chapter presents a few selected protocols that can be performed at any wet chemistry laboratory to purify and biofunctionalize CNTs. The preparation of CNTs modified with metallic nanoparticles, especially gold, is also described since biomolecules can bind and self-organize on the surfaces of such metal-decorated CNTs.
Publication date
PublisherHumana Press, Springer
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedYes
NRC number53388
NPARC number19040615
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Record identifier81d64382-dff2-455f-b0b5-c89e77e17a6e
Record created2012-03-06
Record modified2016-05-09
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