High-pressure gas phase femtosecond laser ionization mass spectrometry

Download
  1. (PDF, 426 KB)
  2. Get@NRC: High-pressure gas phase femtosecond laser ionization mass spectrometry (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1021/ac300743k
AuthorSearch for: ; Search for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titleAnalytical Chemistry
Volume84
Issue13
Pages56335640; # of pages: 8
AbstractWe describe a novel ion source for analytical mass spectrometry based on femtosecond laser ionization at pressures at and above atmospheric and characterize its performance when coupled to a tandem quadrupole/time-of-flight mass spectrometer. We assess source saturation limits, ionization and sampling efficiencies, the effective ionization volume, and limits of detection. We demonstrate 100% efficient ionization for a set of organic compounds and show that the degree of ion fragmentation over a range of laser powers is favorable compared to electron impact ionization, especially in that a substantial parent ion signal is always observed. We show how collisional cooling plays a role in controlling fragmentation at high pressures and address how ion–molecule chemistry can be controlled or exploited. High-pressure femtosecond laser ionization will allow “universal” and efficient ionization, presenting a research direction that will broaden the options for gas phase analysis beyond the capabilities of electron impact ionization.
Publication date
PublisherAmerican Chemical Society
LanguageEnglish
AffiliationSecurity and Disruptive Technologies; National Research Council Canada
Peer reviewedYes
NPARC number21268078
Export citationExport as RIS
Report a correctionReport a correction
Record identifier8c0691b7-362f-4e8b-bc8f-39e7fc7b6c62
Record created2013-04-08
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)