Characterization of phlorotannins from brown algae by LC-HRMS

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DOIResolve DOI: http://doi.org/10.1007/978-1-4939-2684-8_16
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EditorSearch for: Stengel, Dagmar B.; Search for: Connan, Solène
TypeBook Chapter
Book titleNatural Products From Marine Algae
Series titleMethods in Molecular Biology
ISSN1064-3745
ISBN978-1-4939-2684-8
Pages253266; # of pages: 14
SubjectBrown seaweed; High-resolution mass spectrometry; Hydrophilic interaction liquid chromatography; Phlorotannins; Polyphenols
AbstractPhlorotannins are a class of polyphenols found in brown seaweeds that have significant potential for use as therapeutics, owing to their wide range of bioactivities. Molecular characterization of phlorotannin-enriched extracts is challenging due to the extreme sample complexity and the wide range of molecular weights observed. Herein, we describe a method for characterizing phlorotannins employing ultrahigh-pressure liquid chromatography (UHPLC) operating in hydrophilic interaction liquid chromatography (HILIC) mode combined with high-resolution mass spectrometry (HRMS).
Publication date
LanguageEnglish
AffiliationMeasurement Science and Standards; Aquatic and Crop Resource Development; National Research Council Canada
Peer reviewedNo
NRC number56154
NPARC number21275905
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Record identifier8ca11abb-23cf-4c96-9c6a-be428224f8ed
Record created2015-07-31
Record modified2016-05-09
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