High-throughput chemistry toward complex carbohydrates and carbohydrate-like compounds

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TypeArticle
Journal titleCombinatorial Chemistry & High Throughput Screening
ISSN1386-2073
Volume5
Issue2
Pages179193; # of pages: 15
SubjectCarbohydrates; carbohydrate-like compounds; biomolecules; carbohydrate conjugates; glycoproteins; glycolipids; oligosaccharides; carbodrate scaffolida; multiple component condensation (mcc); glycohybrids; amino acids; carbohydrate conformation; carbohydrate sequence; combinatorial chemistry techniques; glycosylation; molecular sequence data
AbstractIn the area of peptide and nucleic acid chemistry and biology, high-throughput synthesis has played an important role in providing useful small-molecule-based chemical probes in understanding the structure and function relationships. The past several years, there has been a constant rise in interest toward understanding the biological roles and functions of another important class of biomolecules, i.e., carbohydrates and carbohydrate conjugates. Although at early stages, in recent years, several groups have developed high-throughput synthetic methods to obtain complex carbohydrates or carbohydrate-like smallmolecules. The present review article summarizes some of these developments.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Steacie Institute for Molecular Sciences
Peer reviewedNo
Identifier18319658
NPARC number12327400
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Record identifier8d43f475-ff36-43d2-80d3-00ad6375618a
Record created2009-09-10
Record modified2016-05-09
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