Electronic dynamic cellular sensor used to measure gold nanoparticles enhanced radiotherapy

DOIResolve DOI: http://doi.org/10.1109/LISSA.2011.5754145
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Proceedings title2011 IEEE/NIH Life Science Systems and Applications Workshop (LiSSA)
Conference2011 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2011, April 7-8, 2011, Bethesda, MD, USA
Article number5754145
Pages2023; # of pages: 4
SubjectCancer cells; Cell effects; Cellular monitoring; Clonogenic assays; Dynamic changes; Dynamic data; Dynamic monitoring; Electronic dynamics; Gold Nanoparticles; In-vitro; MTT assays; Radiation therapy; Real time; Real time monitoring; Time points; Monitoring; Nanoparticles; Sensors; Radiotherapy
AbstractConventional cellular test, such as clonogenic assay and MTT assay, can only be used to determine the cell effects at one certain time point and impossible for dynamic monitoring. Real time electronic cellular sensor (RT-CES) has been developed for real-time and dynamic cellular monitoring. In this paper, we described how to use RT-CES for real-time monitoring the dynamic change induced by the toxicants and radiotherapy. The gold nanoparticles enhanced radiotherapy was evaluated. Radiation therapy resistance was measured in real time and the dynamic data were used to guide radiotherapy on cancer cells in vitro. © 2011 IEEE.
Publication date
AffiliationNational Research Council Canada (NRC-CNRC); National Institute for Nanotechnology
Peer reviewedYes
NPARC number21271951
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Record identifier922f6471-496e-402e-b887-b2cc7194383a
Record created2014-05-13
Record modified2016-05-09
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