Structural analysis of the lipopolysaccharide from Vibrio cholerae serotype O22: Carbohydr.Res.

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TypeArticle
Journal titleCarbohydr.Res.
Volume304
Issue3-4
Pages191208; # of pages: 18
Subjectanalysis; Canada; Carbohydrate Conformation; Carbohydrate Sequence; chemical; chemistry; classification; Cross Reactions; ELUCIDATION; immunology; isolation & purification; LIPOPOLYSACCHARIDE; Lipopolysaccharides; LPS; MAGNETIC; MAGNETIC-RESONANCE; Mass Fragmentography; mass spectrometry; MASS-SPECTROMETRY; Methylation; Molecular Sequence Data; MOLECULE; NMR; NUCLEAR; Nuclear Magnetic Resonance; Nuclear Magnetic Resonance,Biomolecular; NUCLEAR-MAGNETIC-RESONANCE; RESONANCE; SEROTYPE; SPECTROSCOPY; STRAIN; STRUCTURAL; structural analysis; STRUCTURAL-ANALYSIS; structure; Vibrio; Vibrio cholerae
AbstractThe structure of the lipopolysaccharide (LPS) from Vibrio cholerae serogroup O22 was elucidated. The LPS was subjected to a variety of degradative procedures, and the structures of the purified products were established by monosaccharide and methylation analyses, nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry. The following structure for the complete LPS molecule was determined on the basis of the combined data from these experiments. [formula: see text] The elucidation of this structure provided a chemical basis for the serological cross-reactions observed between this strain and V. cholerae serogroup O139
Publication date
LanguageEnglish
AffiliationNRC Institute for Biological Sciences; National Research Council Canada
Peer reviewedNo
NRC numberCOX1997
NPARC number9386739
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Record identifier97aa3cb2-bfa0-476a-8e0b-99c6c2fe2dfa
Record created2009-07-10
Record modified2016-05-09
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