Assessment of tissue viability by near-IR spectroscopy and imaging

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DOIResolve DOI: http://doi.org/10.1117/12.306084
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TypeArticle
Proceedings titleInfrared Spectroscopy: New Tool in Medicine
Series titleProceedings of SPIE; no. 3257
ConferenceInfrared Spectroscopy : New Tool in Medicine, January 27, 1998, San Jose, California, U.S.A.
ISSN0277-786X
Pages199207; # of pages: 9
Subjectnear infrared multispectral imaging; near infrared spectroscopy; hemoglobin oxygen saturation; tissue perfusion; skin flap
AbstractNear IR diffuse reflectance spectroscopy and imaging are used to assess tissue status following reconstructive surgery. Utilizing the differential absorption of oxy- and deoxy-hemoglobin between 670-1100 nm, tissue hemoglobin oxygen saturation changes were monitored in reverse McFarlane dorsal rat skin flaps. Significant changes in these parameters were observed upon surgical elevation of the skin flap. A significant regional variation along the skin flap was also observed. The magnitude of the drop is tissue oxygen saturation, as observed immediately following surgery, correlated with the final clinical outcome of the flap tissue. These results indicate the potential of near IR spectroscopy and imaging to monitor tissue oxygenation status and assess tissue viability following reconstructive surgery.
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PublisherSPIE
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Biodiagnostics
Peer reviewedNo
NRC number891
NPARC number9742383
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Record identifier9a728441-1020-446c-a8df-1ae7e790754f
Record created2009-07-17
Record modified2017-09-13
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