Hybrid Unsupervised/Supervised Virtual Reality Spaces for Visualizing Gastric and Liver Cancer Databases: An Evolutionary Computation Approach

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TypeArticle
ConferenceThe 17th International Symposium on Methodologies for Intelligent Systems (ISMIS 2008), May 20-23, 2008., Toronto, Canada
AbstractThis paper expands a multi-objective optimization approach to the problem of computing virtual reality spaces for the visual representation of relational structures (e.g. databases), symbolic knowledge and others, in the context of visual data mining and knowledge discovery. Procedures based on evolutionary computation are discussed. In particular, the NSGA-II algorithm is used as a framework for an instance of this methodology; simultaneously minimizing Sammon's error for dissimilarity measures, and mean cross-validation error on a k-nn pattern classifier. The proposed approach is illustrated with two examples from cancer genomics data (e.g. gastric and liver cancer) by constructing virtual reality spaces resulting from multi-objective optimization. Selected solutions along the Pareto front approximation are used as nonlinearly transformed features for new spaces that compromise similarity structure preservation (from an unsupervised perspective) and class separability (from a supervised pattern recognition perspective), simultaneously. The possibility of spanning a range of solutions between these two important goals, is a benefit for the knowledge discovery and data understanding process. The quality of the set of discovered solutions is superior to the ones obtained separately, from the point of view of visual data mining.
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LanguageEnglish
AffiliationNRC Institute for Information Technology; National Research Council Canada
Peer reviewedNo
NRC number49896
NPARC number8913854
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Record identifiera0001408-8da6-47f1-a170-89b1eb6603b5
Record created2009-04-22
Record modified2016-05-09
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