Insect resistance to Bacillus thuringiensis: uniform or diverse?

DOIResolve DOI: http://doi.org/10.1098/rstb.1998.0327
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TypeArticle
Volume353
Issue1376
Pages17511756; # of pages: 6
Subjectenv; allelism; Bacillus thuringiensis; diamondback moth; evolution; genetic variation; resistance
AbstractResistance to the insecticidal proteins produced by the soil bacterium Bacillus thuringiensis (Bt) has been documented in more than a dozen species of insect. Nearly all of these cases have been produced primarily by selection in the laboratory, but one pest, the diamondback moth (Plutella xylostella), has evolved resistance in open-¢eld populations. Insect resistance to Bt has immediate and widespread signi¢cance because of increasing reliance on Bt toxins in genetically engineered crops and conventional sprays. Furthermore, intense interest in Bt provides an opportunity to examine the extent to which evolutionary pathways to resistance vary among and within species of insect. One mode of resistance to Bt is characterized by more than 500-fold resistance to at least one Cry1A toxin, recessive inheritance, little or no cross-resistance to Cry1C, and reduced binding of at least one Cry1A toxin. Analysis of resistance to Bt in the diamondback moth and two other species of moths suggests that although this particular mode of resistance may be the most common, it is not the only means by which insects can attain resistance to Bt.
Publication date
LanguageEnglish
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedNo
NRC number41790
NPARC number3538877
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Record identifiera442cde1-b26d-4a9a-8039-9acb5f7859e3
Record created2009-03-01
Record modified2016-05-09
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