Occurrence and biological activities of eremophilane-type sesquiterpenes

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DOIResolve DOI: http://doi.org/10.2174/1389557514666140820105422
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TypeArticle
Journal titleMini-Reviews in Medicinal Chemistry
ISSN1389-5575
Volume14
Issue8
Pages664677; # of pages: 14
Subjectanti-tumor; anti-microbial; anti-inflammatory; anti-allergy; eremophilane-type sesquiterpenes
AbstractAs important members of the terpenes family, sesquiterpenes represent a group of natural compounds with diverse skeletal types. Among them, the eremophilane-type sesquiterpenes, widely present in several genera (such as Ligularia, Senecio, Cacalia) of Asteraceae, account for a small number of natural compounds and form differently from other sesquiterpenes because they challenged the isoprene rule of biosynthesis. Due to the unique structural features and various functional groups, these compounds possess a number of biological activities such as anti-tumor, anti-bacterial and anti-inflammatory, having received increasing interest in the recent years. This review summarizes the occurrence of eremophilane-type sesquiterpenes and research progresses on their biological activities since the 1990s.
Publication date
PublisherBentham Science Publishers
LanguageEnglish
AffiliationNational Research Council Canada; National Institute for Nanotechnology; Aquatic and Crop Resource Development
Peer reviewedYes
NPARC number21272896
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Record identifierad4a0b78-e41e-4a26-a341-be232dd7b40b
Record created2014-12-03
Record modified2016-05-09
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