Morphogenesis in Candida albicans

DOIResolve DOI: http://doi.org/10.1146/annurev.micro.61.080706.093341
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TypeArticle
Volume61
Pages529553; # of pages: 25
SubjectBiotechnology; Candida; Candida albicans; Cells; Human; Morphogenesis; pha; Protein; Proteins; Stress; Yeast
AbstractCandida albicans is termed a dimorphic fungus because it proliferates in either a yeast form or a hyphal form. The switch between these forms is the result of a complex interplay of external and internal factors and is coordinated in part by polarity-regulating proteins that are conserved among eukaryotic cells. However, yeast and hyphal cells are not the only morphological states of C. albicans. The opaque form required for mating, the pseudohyphal cell, and the chlamydospore represent distinct cell types that form in response to specific genetic or environmental conditions. In addition, hyperextended buds can form as a result of various cell cycle-related stresses. Recent studies are beginning to shed light on some of the molecular controls regulating the various morphogenetic forms of this fascinating human pathogen
Publication date
LanguageEnglish
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedNo
NRC number47550
NPARC number3539434
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Record identifierae334bdc-42ea-456a-bf36-7feaf5b90da8
Record created2009-03-01
Record modified2016-05-09
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