Carrier molecules for use in veterinary vaccines

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Journal titleVaccine
Pages596602; # of pages: 7
Subjectalginic acid; chitosan; CpG oligodeoxynucleotide; DNA vaccine; drug carrier; gamma interferon; glycoconjugate; glycoconjugate vaccine; Haemophilus vaccine; hepatitis B surface antigen; immunoglobulin A; immunoglobulin G1; immunoglobulin G2; immunoglobulin M; immunostimulating agent; influenza vaccine; interleukin 2; interleukin 6; liposome; nanoparticle; peptide vaccine; poly[di(sodium carboxylatoethylphenoxy] phosphazene; poly[di(sodium carboxylatophenoxy)] polyphosphazene; polyglactin; polymer; polysaccharide vaccine; starch; unclassified drug; vaccine; Wart virus vaccine; Actinobacillus pleuropneumoniae; antigen presenting cell; atrophic rhinitis; bacterial load; Bordetella bronchiseptica; bronchopneumonia; CD8+ T lymphocyte; cost effectiveness analysis; cytokine production; cytotoxic T lymphocyte; dendritic cell; Haemophilus influenzae type b; human; Human papillomavirus type 16; immunization; immunogenicity; mucosal immunity; Neisseria meningitidis; nonhuman; Pasteurella multocida infection; priority journal; review; Streptococcus pneumoniae; virus like agent; Animals; Glycoconjugates; Nanoparticles; Vaccination; Vaccines; Vaccines, Conjugate; Vaccines, Subunit; Vaccines, Virus-Like Particle
AbstractThe practice of immunization of animals and humans has been carried out for centuries and is generally accepted as the most cost effective and sustainable method of infectious disease control. Over the past 20 years there have been significant changes in our ability to produce antigens by conventional extraction and purification, recombinant DNA and synthesis. However, many of these products need to be combined with carrier molecules to generate optimal immune responses. This review covers selected topics in the development of carrier technologies for use in the veterinary vaccine field, including glycoconjugate and peptide vaccines, microparticle and nanoparticle formulations, and finally virus-like particles. © 2012.
Publication date
AffiliationNational Research Council Canada (NRC-CNRC)
Peer reviewedYes
NPARC number21270587
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Record identifierae945c23-371e-467a-a9fd-4b5aa6ba079d
Record created2014-02-17
Record modified2016-05-09
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