Influence of slow versus fast increases in core temperature on prolactin and TNF-alpha

  1. Get@NRC: Influence of slow versus fast increases in core temperature on prolactin and TNF-alpha (Opens in a new window)
DOIResolve DOI:
AuthorSearch for: ; Search for: ; Search for:
Proceedings titleMedicine and Science in Sports and Exercise
ConferenceAmerican College of Sports Medicine (ACSM) 58th Annual Meeting, May 31st-June 4th, 2011, Denver, CO
AbstractProlactin (PRL), a pituitary hormone regulated by neurons in the hypothalamus, has been suggested as an indicator of fatigue during exercise-induced hyperthermia (EIH) given its strong relationship with body core temperature (Tco). However, the strength of this relationship during different rates of Tco increase and subsequent recovery are unknown. In addition, given the influence that systemic inflammatory cytokines, such as Tumor necrosis factor (TNF)-α, have on the pituitary gland; it would be of interest to determine the relationship between PRL and TNF-α during EIH. PURPOSE: To examine the PRL and TNF-α heat stress responses during low (slow heating) and moderate (fast heating) exercise intensities and subsequent resting or cold water immersion recovery. METHODS: Seven trained individuals (5 males, 2 females, mean ± SE: 27.0 ± 3.3 yrs, 57.9 ± 2.2 mL·kg⁻¹nim·⁻¹, 18.5 ± 2.4 % fat) underwent 4 EIH sessions (40°C, 30% R.H.) on a treadmill to a rectal temperature (Tre), measured continuously, of 39.5°C while wearing an impermeable rain suit followed by upright seated resting or 2°C ice-water immersion recovery. Venous blood was obtained at rest (PRE; prior to exercise), during exercise (Tre 38, 39, 39.5°C), the start of recovery (5 min post 39.5°C), and subsequent recovery (Tre 39, 38°C). PRL and TNF-α (high sensitivity) were measured by an ELISA and corrected for changes in plasma volume.
Publication date
PublisherAmerican College of Sports Medicine / Wolters Kluwer
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NPARC number23001376
Export citationExport as RIS
Report a correctionReport a correction
Record identifieraea3b9b9-6a75-4529-a393-bad811964a50
Record created2017-01-27
Record modified2017-02-23
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)