The relationship between the serogroup antigen and lipopolysaccharide of Legionella pneumophila

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TypeArticle
Journal titleThe Journal of hygiene
Volume96
Issue1
Pages3948; # of pages: 10
Subjectantibodies, bacterial/analysis; antigens, bacterial/analysis; electrophoresis, polyacrylamide gel; enzyme-linked immunosorbent assay; humans; legionella/classification; legionella/immunology; legionella/isolation & purification; lipopolysaccharides/analysis; serotyping; species specificity
AbstractSerogroup-specific antigen was extracted from a number of Legionella pneumophila strains and compared with phenol-water extracted lipopolysaccharide on the basis of gel filtration, chemical analysis, SDS-PAGE and reaction with serogroup-specific antibody in immunoblots. Serogroup specificity is apparently borne by the O side-chains of the lipopolysaccharide, which, although smooth in type, partitions in the phenol phase. For four serogroup 1 strains tested, there was no qualitative correlation between O side-chain length and pulmonary virulence for guinea-pigs.
Publication date
Linkhttp://www.jstor.org/stable/3863100
LanguageEnglish
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NRC numberCONLAN1986
NPARC number9382845
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Record identifierb8039567-d7de-4729-8200-56c70357d9d3
Record created2009-07-10
Record modified2016-05-09
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