Advances in radical-trapping antioxidant chemistry in the 21st century: A kinetics and mechanisms perspective

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DOIResolve DOI: http://doi.org/10.1021/cr500226n
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TypeArticle
Journal titleChemical Reviews
ISSN0009-2665
Volume114
Issue18
Pages90229046; # of pages: 25
SubjectIndustrial research; Structural optimization; 20th century; Anti-oxidant chemistry; Commercial perspectives; Degenerative disease; Kinetics and mechanism; Optimal performance; Radical trapping; Synergistic interaction; Antioxidants
AbstractAntioxidants were divided in two parts radical-trapping antioxidants (RTAs) and preventive antioxidants. By the final quarter of the 20th century, the commercial importance of antioxidants was overshadowed by their putative role in human health, as the implication of radical-mediated oxidation in virtually all types of degenerative diseases, including cancer and aging, emerged. From a commercial perspective, there continues to be significant interest in the development of RTA technology. Much of the industrial research effort has been on optimization of the structures of existing RTAs to provide appropriate physical properties and identification of combinations of existing RTAs that achieve optimal performance via the synergistic interactions.
Publication date
PublisherACS Publishing
LanguageEnglish
AffiliationNational Research Council Canada; Security and Disruptive Technologies
Peer reviewedYes
NPARC number21275468
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Record identifierbe52eb53-3488-492c-8d10-f6d56d0a36e5
Record created2015-07-14
Record modified2016-05-09
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