MicroRNA regulation and interspecific variation of gene expression

Download
  1. Get@NRC: MicroRNA regulation and interspecific variation of gene expression (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1016/j.tig.2007-04-003
AuthorSearch for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titleTRENDS in Genetics
Volume23
Issue8
Pages372375; # of pages: 4
SubjectBiotechnology; Gene Expression; Genes; genome; pha
AbstractMicroRNAs (miRNAs) modulate expression of their target genes in various tissues and at different developmental stages, but it is unclear whether they drive cross-species variation in gene expression. By comparing data from mammal and fly species we found that the cross-species expression variation of miRNA targets is significantly lower than that of other genes. This implies that miRNAs can affect gene expression by reducing stochastic noise, buffering cross-species variation and constraining evolutionary gene expression variation
Publication date
LanguageEnglish
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedNo
NRC number47563
NPARC number3539530
Export citationExport as RIS
Report a correctionReport a correction
Record identifierc1a3a3b5-f404-4fbb-adaf-cc0a23243480
Record created2009-03-01
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)