Infrared spectroscopic characterization of human white matter, grey matter and multiple sclerosis lesions

DOIResolve DOI: http://doi.org/10.1117/12.166686
AuthorSearch for: ; Search for: ; Search for: ; Search for:
TypeBook Chapter
Proceedings title9th International Conference on Fourier Transform Spectroscopy
Series titleSPIE - International Society for Optical Engineering. Proceedings
Conference9th International Conference on Fourier Transform Spectroscopy, August 23, 1993, Calgary, Alberta, Canada
Volume2089
Pages494495; # of pages: 2
AbstractFT-IR spectroscopy has been used to characterize white matter, grey matter, and multiple sclerosis (MS) plaques from human central nervous system (CNS) tissue. Discrimination among these three tissue types is possible due to variations in composition. Spectra of white matter exhibit strong lipid absorptions. In contrast, spectra of grey matter reveal a reduced lipid contribution and a significant absorption from water. MS plaques exhibit spectra indicative of lipid loss and, depending upon whether the plaques are chronic or acute, changes in the protein and/or water content.
Publication date
PublisherSPIE
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Biodiagnostics
Peer reviewedYes
NRC number773
NPARC number9742229
Export citationExport as RIS
Report a correctionReport a correction
Record identifierc496fb9c-1f5a-419f-badd-b5cb3bb6ee29
Record created2009-07-17
Record modified2017-04-24
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)