An IR spectroscopic characterization of the blood component platelet activating factor

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DOIResolve DOI: http://doi.org/10.1117/12.970751
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TypeBook Chapter
Proceedings titleFourier and Computerized Infrared Spectroscopy
Series titleSPIE Proceedings
ConferenceFourier and Computerized Infrared Spectroscopy, January 1, 1985, Ottawa, Canada
ISSN0277-786X
Volume553
Pages163164
AbstractThe platelet activating factor, PAF, has been recently identified as an ether lipid with dramatic bioreactivity. The present IR spectroscopic investigation demonstrates that in an aqueous environment PAF can assume three different structures, a micellar form at tempera-tures above 21°C, a solid-like opaque lamellar form at temperatures below 12°C, and an intermediate transparent lamellar form that exists at temperatures between 12 and 21°C. The three structures are separated by two reversible phase transitions; however, the rate of the reversed micellar to lamellar change is negatively temperature dependent, i.e., about 6 min at -1°C and 12 min at 3°C, and slower than the lamellar to micellar change.
Publication date
PublisherSPIE
LanguageEnglish
AffiliationNational Research Council Canada
Peer reviewedYes
NPARC number23001103
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Record identifierc9833066-efee-4035-8ad9-c05cd8df64d4
Record created2016-12-13
Record modified2016-12-13
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