Suction-enhanced siphon valves for centrifugal microfluidic platforms

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DOIResolve DOI: http://doi.org/10.1007/s10404-011-0878-2
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TypeArticle
Journal titleMicrofluidics and Nanofluidics
ISSN1613-4982
1613-4990
Volume12
Issue1-4
Pages345354; # of pages: 10
SubjectCentrifugal microfluidics; Centrifugal; suction effect; Suction-enhanced siphoning; Hydrophobic fluidics; Siphoning; Valving
AbstractIn traditional centrifugal microfluidic platforms pumping is restricted to outward fluid flow, resulting in potential real estate issues for embedding complex microsystems. To overcome the limitation, researchers utilize hydrophilic channels to force liquids short distances back toward the disk center. However, most polymers used for CD fabrication are natively hydrophobic, and creating hydrophilic conditions requires surface treatments/specialized materials that pose unique challenges to manufacturing and use. This work describes a novel technology that enjoys the advantages of hydrophilic fluidics on a hydrophobic disk device constructed from untreated polycarbonate plastic. The method, termed suction-enhanced siphoning, is based on exploiting the non-linear hydrostatic pressure profile and related pressure drop created along the length of a rotating microchannel. Theoretical analysis as well as experimental validation of the system is provided. In addition, we demonstrate the use of the hydrostatic pressure pump as a new method for priming hydrophobic-based siphon structures. The development of such techniques for hydrophobic fluidics advances the capabilities of the centrifugal microfluidic platform while remaining true to the goal of creating disposable polymer devices using feasible manufacturing schemes.
Publication date
LanguageEnglish
AffiliationNRC Industrial Materials Institute; National Research Council Canada
Peer reviewedYes
NPARC number21268377
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Record identifierc9c4295c-2477-4b68-9944-9eacd3e27f7c
Record created2013-07-04
Record modified2016-05-09
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