Organic reducing agents. Reduction of electron deficient bromides by 1,2,2,6,6-pentamethylpiperidine (PMP)/mercaptoethanol

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DOIResolve DOI: http://doi.org/10.1016/0040-4039(95)00697-B
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TypeArticle
Journal titleTetrahedron Letters
Volume36
Issue23
Pages39974000; # of pages: 4
Abstract1,2,2,6,6-pentamethylpiperidine (PMP) is shown to be an effective reducing agent for the radical chain conversion of primary bromoesters to the corresponding esters. The problem of inefficient reduction of tertiary bromoesters in these reactions has been overcome by the addition of an alkyl thiol which mediates the hydrogen atom transfer between the two hindered alkyl centers.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Steacie Institute for Molecular Sciences
Peer reviewedNo
NPARC number12333661
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Record identifiercde0b12a-b648-4407-b3a0-1c85d559ff81
Record created2009-09-10
Record modified2016-05-09
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