Electrical activity of artificial ion channels incorporated into planar lipid bilayers

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DOIResolve DOI: http://doi.org/10.1039/A701060E
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TypeArticle
Journal titleJournal of the Chemical Society, Perkin Transactions
Volume2
Issue8
Pages14691471; # of pages: 3
Subjectenv
AbstractThe ion transport ability in a planar lipid bilayer of a 21 amino acid peptide bearing six 21-crown-7 side chains is reported. The compound was designed to form an artificial ion channel by stacking the crown rings, when adopting an á-helical conformation in a bilayer membrane. All the derivatives of 1 exhibited membrane conductivity with the best results obtained with the unprotected analog 4. The latter showed typical single channel activity.
Publication date
LanguageEnglish
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedNo
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NRC number41770
NPARC number3539977
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Record identifierd0533652-a335-4f9a-b556-16442349996f
Record created2009-03-01
Record modified2016-05-09
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