Maximization of signal-to-noise ratio in optical coherence tomography using a depth-dependent matched filter

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DOIResolve DOI: http://doi.org/10.1117/12.2001691
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TypeArticle
Proceedings titlePhotonics North 2012
Proceedings of SPIE
ConferencePhotonics North 2012, June 6-8, 2012, Montreal, QC, Canada
ISSN0277-786X
ISBN9780819490902
Volume8412
Article number841202
SubjectDepth dependents; Empirical estimate; OCT images; Second order statistics; Time domain; Vascular tissue; Matched filters; Signal to noise ratio; Tissue; Optical tomography
AbstractWe discuss and demonstrate the dependence of noise on the signal in time-domain optical coherence tomography (TD-OCT). We then derive a depth-dependent matched filter to maximize the signal-to-noise ratio at every pixel in a depth-scan (A-scan). We use an empirical estimate of the second order statistics of the noise in OCT images of vascular tissue to implement a depth-dependent filter that is matched to these images. The application of our filter results in an average increase of signal-to-noise ratio of about 7 dB compared to a simple averaging operation. Our filter is not specific to time-domain OCT, but it is applicable to other types of OCT systems.
Publication date
LanguageEnglish
AffiliationMedical Devices; National Research Council Canada
Peer reviewedYes
NPARC number21270176
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Record identifierd21ee184-120e-423f-b645-558967cb203c
Record created2014-01-08
Record modified2016-05-09
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