Genome-wide expression and location analyses of the Candida albicans Tac1p regulon

DOIResolve DOI: http://doi.org/10.1128/EC.00327-07
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TypeArticle
Volume6
Issue11
Pages21222138; # of pages: 17
SubjectCandida; Candida albicans; Genes; Mutation; pha; Zinc
AbstractA major mechanism of azole resistance in Candida albicans is overexpression of the genes encoding the ATP binding cassette transporters Cdr1p and Cdr2p due to gain-of-function mutations in Tac1p, a transcription factor of the zinc cluster family. To identify the Tac1p regulon, we analyzed four matched sets of clinical isolates representing the development of
Publication date
AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedNo
NRC number49522
NPARC number3539371
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Record identifierd2e7b670-7dee-4aca-b717-e541fe4280fa
Record created2009-03-01
Record modified2016-05-09
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